The quality of sex matters a great deal. It strengthens the bonds between partners in couples and raises the self-esteem and the confidence of the people involved. This is why you need to endeavor to give and get the best in bedroom and whenever you feel that your natural capabilities are waning, then consider going for a performance booster such as sildenafil. This substance has been in use for more than two decades − going by the brand name Viagra − and it has proved to be effective in improving sex performance in men with erectile dysfunction dramatically. Today, many people are flocking pharmacists to seek the wonder pills, and manufacturers are doing their best to come up with better versions. The good news is that users can now buy sildenafil online and get around the fears of buying while facing the doctors and pharmacy people.
Sildenafil is a medication that acts by inhibiting an enzyme phosphodiesterase type 5 (PDE 5) which typically acts to degrade cyclic GMP. The role of cyclic GMP, in its turn, is to relax the smooth muscles of the blood vessels in penis so that they can dilate and allow inflow of blood, which later results in an erection.
Simply put, what you see being marketed as oral Viagra has sildenafil citrate as its main active ingredient. Nevertheless, the manufacturers do not just stuff their pills with this compound. Besides the active ingredient, a drug will also have other supporting ingredients that complete the composition and bring out aspects such as solubility, color, and other characteristics.
In the case of Viagra, sildenafil citrate is the active ingredient. This is just a citrate salt of sildenafil which improves its actions of vasodilation to cause and maintain a proper erection. It is this salt that selectively inhibits the cyclic Guanosine Monophosphate (GMP) type 5. In isolation, the sildenafil citrate appears as a white crystalline powder. However, the complete formulation which has sildenafil citrate alongside other chemical compounds is usually a blue pill with a diamond shape (that applies to brand-name Viagra while generic versions may differ in color and shape). The additional ingredients which are also termed as excipients in Viagra include cellulose, calcium phosphate, titanium dioxide and lactose among others. Although these compounds do not have any direct effects on the treatment of erectile dysfunction, they are essential in supporting the functioning of Viagra as a whole. Needless to say, anyone having an allergy to any of the constituents should see a physician before taking the medication.
Maybe you have heard a lot about sildenafil alone, and you are now wondering why they had to make it sildenafil citrate. Just as it has been said in the preceding paragraphs, many other medical conditions are treated by salt forms of the required element. For instance, a patient suffering from hyponatremia − a condition in which sodium levels in the body drop to below normal − requires their sodium stores to be replenished. One of the treatment options for such a case is sodium hydroxide and not just the pure sodium. That is the same principle that applies to the administration of sildenafil citrate in patients with erectile dysfunction.
Pfizer, being the company that discovered sildenafil could be used for treating erectile dysfunction, patented the medication ahead of other companies and for a long time they were the sole manufacturers of sildenafil-based Viagra in the US and many other countries of the world. Today, the patent has expired in several regions and now sildenafil generic is rocking pharmacies as well as general stores. The generic meds are turning out to be a worthy competition to the brand name Viagra. However, learning some differences between these two can be very helpful for a consumer who is still in the dark.
The name Viagra is used by Pfizer and was decided upon by the company when they first manufactured the drug. The generic forms of Viagra are commonly referred to as ‘sildenafil pills’. Pfizer also applied for a patent on the appearance of the brand name Viagra. This trademark appearance of blue, diamond-shaped tabs has earned Viagra an alias, ‘the little blue pill’. Many of the sildenafil generic tabs have other appearances such as white colors with a round or oval shape.
The prices of the generic Viagra pills are also lower compared to the brand name pills. This is mostly brought about by the bills that the first manufacturers had to foot. Going through clinical trials and other phases costs a lot, and that is why these companies deserve a patent for some time. The generic manufacturers, on the other hand, come in when the trials have been done, and all they have to do is come up with a bioequivalent formulation of a drug that borrows a lot from the first manufacturer. This is why they sell at lower prices. Moreover, generic manufacturers are many, and they try to outcompete each other by offering the best deals in terms of prices.
All in all, the brand name and the generic Viagra both have the same active ingredient which is sildenafil, and as such, it is expected that these meds do not have wide variations. As long as a generic drug has been approved by the authorities, for example, the FDA in the US, then it is safe for use. The effectiveness and the side effects are very similar.
Sildenafil was manufactured as a prescription-only med because of its potential to be abused and some other adverse effects that it may have to certain groups of patients. However, the generic manufacturers tend not to be too stringent like Pfizer. You can buy the generic forms from some sellers without a prescription thanks to the makers’ quest to attract many buyers who are not ready to see a doctor for a diagnosis and prescription.
Many people wouldn’t want to sit across a desk with a physician on the other side, asking them questions and taking their history. So buying sildenafil over the counter has become a viable option, and they will run for the opportunity to obtain the meds that easily. With online buying coming into the picture, over the counter purchases are even more convenient.
One and the major advantage of buying sildenafil over the counter is that you don’t need a prescription. Just make an order and have your supply of ED pills with you within days, hours or even minutes if you decide to go for a brick-and-mortar store. The process is quick. You don’t have to incur extra costs in paying a doctor to get you a prescription and, more importantly, you don’t have to discuss your sexual problems with them.
On the other hand, you have to be careful when doing over the counter purchases. Make sure that you are buying safe meds that will actually treat ED… But how do you do this? The answer is simple: ensure you buy from a trusted vendor. Also, check if the drugs have been approved by the relevant authorities.
If you are a US citizen, then buying sildenafil over the counter in your home country will be a violation of the rules but you can go around this by buying from other countries. When you are traveling to a country that allows over the counter purchases of sildenafil, you can grab yourself a couple of packages and carry them back home. However, this will only be doable if you want to take small amounts just for your own use in a particular period of time. If you want to carry bulk, you will probably have a problem dealing with the authorities and proving that all this sildenafil you’ve got on you in not intended for sale.
Some of the countries that allow buying sildenafil over the counter include the UK, Russia, Mexico and many countries in Asia and Africa. Sildenafil 50mg
Sildenafil comes in different strengths and one of them, which is also the most commonly used, is the sildenafil 50mg. This is the medium strength and it is what most users start with. If one responds well to this dosage, then they will be maintained on it. However, if the response is not optimum, then a physician can advise for a change of the dosage, either going up or down, judging from the circumstances.
For those who might be experiencing some adverse effects with the sildenafil 50 mg, the dosage is usually lowered to sildenafil 20 mg, and their situation is monitored closely. This is also the dosage that is used for people who have health conditions that may not tolerate higher doses of sildenafil. The older populations and those having liver and renal problems are considered for this lower strength treatment. Even some medications may prompt lowering of the dose to this strength. An example is ritonavir which tends to increase the levels of sildenafil in blood. Therefore, patients on this antiviral should be kept on the 20mg sildenafil dose. They should not take sildenafil more frequently than once in 48 hours. Other drugs that raise the plasma levels of sildenafil include ketoconazole and erythromycin which inhibit CYP3A4.
Sildenafil citrate 100mg is the maximum acceptable strength of the med. It becomes an option when an individual shows a weak response to the 50mg pills. It is upon the physician to decide whether to raise the dose, keep it constant or lower it because these adjustments have possible implications on the health of an individual.How to Buy Sildenafil Online Risk-Free
While buying sildenafil online might be so thrilling, you need to take certain precautions to avoid landing in a ditch and going through what some consumers have experienced. The online platform is marred with all kinds of wrongs, but you can stay on the safe side and avoid being a victim. Here’s how to buy online sildenafil without any risks.
First, ensure that you are buying from a trusted vendor. A good option would be a known supplier, who is well established with credible customer care services and a supply network. If you are buying the generic pills, make sure they are legit. They should be certified by the authorities. Also, check out the reviews on the website that you are buying from.
When purchasing from abroad, make sure that the seller supplies to your country. Go through the import policies in your homeland to ensure that they allow importation of erection medications.
Buying online erectile dysfunction pills is not only convenient but also cheaper. The sellers use the bulk discounts they obtain to lower the sellout prices. What’s more, the drugs will be delivered to you, and you don’t have to go through the trouble of driving to a pharmacy and queuing.
Sildenafil has been used for a long as an erection medication, and its fame hasn’t faded. It is currently the most widely used ED med in the world and its popularity keep growing, especially with the mushrooming of generic manufacturers.